What is the function of albumin
Albumin is the most abundant protein in human plasma, accounting for about 50%-60% of the total plasma protein. It plays a variety of important roles in maintaining human health. In recent years, the application and research results of albumin have become a hot topic in the medical field. This article will discuss the role of albumin and its clinical application in the past 10 days of hot topics on the entire network.
1. The basic functions of albumin
Albumin is mainly synthesized by the liver and has the following core functions:
| Function Type | Specific functions |
|---|---|
| Maintain colloid osmotic pressure | Accounts for 75%-80% of the total plasma osmotic pressure to prevent tissue edema |
| Transport function | Combining and transporting hormones, drugs, fatty acids and other substances |
| Nutritional support | Provide amino acid reserves and participate in protein synthesis |
| Antioxidant effects | Contains free thiol groups, which can scavenge free radicals |
| Buffer function | Regulate blood pH |
2. Important role in clinical application
According to recent medical research and clinical data, albumin has important application value in the following fields:
| Application areas | Mechanism of action | Clinical effect |
|---|---|---|
| Cirrhosis | Improve hypoalbuminemia and reduce ascites | Reduce mortality rate by 38% in 28 days |
| Burn treatment | Maintain blood vessel content to prevent shock | Increase cure rate by about 25% |
| Nephrotic syndrome | Supplement lost albumin | Improve edema symptoms |
| Heart surgery | Maintain hemodynamic stability | Reduce postoperative complications |
| Coronavirus disease | Improve microcirculation disorders | Reduce the mortality rate of severely ill patients |
III. The clinical significance of albumin level
Serum albumin levels are an important indicator of apparent health:
| Albumin level (g/dL) | Clinical significance |
|---|---|
| >3.5 | Normal range |
| 2.8-3.5 | Mild lack |
| 2.1-2.7 | Moderate lack |
| <2.1 | Severe lack |
4. Precautions for supplementing albumin
Although albumin has many benefits, it is important to note when using:
1.Indications limitations: Only used for severe hypoalbuminemia (<2.5g/dL) or specific clinical conditions
2.Dose control: The daily dose of general adults precedented between 25-75g
3.Adverse reactions: May cause allergic reactions, excessive capacity load, etc.
4.Taboo people: Use with caution in patients with severe anemia and heart failure
5. Latest research progress
According to the research results published in the past 10 days, the following new findings in the field of albumin:
1. Breakthroughs in recombinant albumin technology may replace human albumin
2. Albumin-drug conjugates show potential in tumor-targeted therapy
3. Albumin nanoparticles have become a hot topic in research on drug delivery systems
4. Progress in predicting albumin therapy with artificial intelligence
6. How to naturally increase albumin levels
For mild albumin reduction, it can be improved by:
| method | Specific measures |
|---|---|
| Dietary adjustment | Increase high-quality protein intake (eggs, lean meat, soy products) |
| Nutritional supplements | Supplementary branched chain amino acids |
| Liver function protection | Avoid alcohol and control drug use |
| Disease Management | Actively treat primary diseases |
As an important functional protein in the human body, its value is not only reflected in traditional clinical applications, but also with the development of science and technology, its application prospects in the field of medicine will be broader. It is recommended that people with relevant health problems use albumin preparations reasonably under the guidance of a doctor.
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